The Entry Builder is a model kit for the quick construction of organic molecules with "Point and Click" ease.The Entry Builder includes 20 basic building blocks, or atomic fragments, to simplify molecular assembly (top). Also included are libraries of common molecular Groups and Rings (e.g., "Phenanthryl") (middle).At the bottom of each Builder is a set of tool-buttons for making and breaking bonds, deleting atoms, and rapidly minimizing the molecular structure. These Builder panels can be moved at will.

The Expert Builder is a model kit for the quick construction of organics and organometallics, and transition metal compounds with the same "Point and Click" ease provided by the Entry Builder.The Expert Builder includes 64
element buttons and, in UNIX SPARTAN 5.0, an entry box for additional elements (top). Also included are libraries of Groups, Rings, and Ligands (e.g., Benzene), ten hybridization buttons, and bond-number tools (middle).At the bottom of the panel is a set of tool-buttons for making and breaking bonds, deleting atoms, and rapidly minimizing the molecular structure. These Builder panels can be moved at will.

The Peptide Builder is a model kit for the quick construction of polypeptides with the same "Point and Click" ease provided by the other Builders.The Peptide Builder includes 20 natural amino acids to simplify polypeptide assembly (middle), which may be previewed (top). Stereoisomers are also available. Also included is the ability to rapidly build polypeptides using the "Build Sequence" option.At the bottom of each Builder is a set of tool-buttons for making and breaking bonds, deleting atoms, and rapidly minimizing the molecular structure. These Builder panels can be moved at will.

The Nucleotide builder allows for the rapid building of single- and double-stranded DNA and RNA with just a few clicks of the mouse. Related displays will (eventually) include ribbon graphics for easier viewing of large strands.The Nucleotide Builder includes template buttons for the four naturally occuring nucleotide bases (Adenine, Guanine, Thymine, and Cytosine), which may be assembled individually or in groups using the "Build Sequence" tool. Conversion from DNA to RNA (and vice-versa) is just a click away.At the bottom of each Builder is a set of tool-buttons for making and breaking bonds, deleting atoms, and rapidly minimizing the molecular structure. These Builder panels can be moved and resized at will.

The Library builder grants instant access your own libraries of molecules and molecular fragments. This makes building easier and faster than ever before. Included is a library of transition states for common organic reactions.The Library Builder includes a 3D preview screen (top) by which you may manipulate fragments to determine valence-selection and orientation prior to using them on the main screen. The bottom and middle parts of the builder comprise file and folder directory menus for easy navigation through the libraries on your computer or network.At the bottom of the Builder is a set of tool-buttons for making and breaking bonds, deleting atoms, and rapidly minimizing the molecular structure. These Builder panels can be moved at will.

Note: Builders vary by software package. The Builder shown here is from Spartan 5.0.